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What are the future directions of biomonitoring? Biomonitoring of large numbers of chemicals in representative
human populations is just beginning. In these early stages, the aim is
to assess the current levels of natural and synthetic chemicals in human
tissues and fluids and to provide the data for decision-making about future
research needs. The information that is being gathered will be used mainly
to: (1) establish baseline and reference levels for environmental chemicals,
(2) identify chemicals for which appropriate toxicological and environmental
data are lacking, and (3) refine future biomonitoring efforts. The results of the biomonitoring studies will be used
to establish background levels against which to compare future monitoring
results. As more chemicals are added to the biomonitoring studies, a broader
picture of the characteristics of any exposures that are occurring can
be developed. In addition, the impacts of various policies on these exposures
can be evaluated. Further, the background levels obtained can serve as
reference values for use in identifying individuals who may be experiencing
above normal exposures and who may benefit from medical intervention or
treatment. Another outcome of biomonitoring is that it may
reveal the presence of compounds that are not expected and for which
limited toxicological and/or environmental fate data are available.
If the levels of such substances are high enough, this information is
likely to lead to increased research on the properties and effects of
these compounds. In summary, the results of biomonitoring can help to suggest which environmental compounds are of most importance, what the background and reference levels for these compounds are, and which segments of the population may be the most highly exposed. Each of these outcomes will lead to further study aimed at refining estimates of exposure, identifying sources, identifying population segments most highly exposed, and assessing the impacts of steps taken to reduce exposure. Thus, biomonitoring can contribute to research that alerts scientists, regulators, and the public to possible risks and also allays fears that might arise from the knowledge that large numbers of natural and synthetic chemicals are present in our bodies. |
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